Info
This antibody is included in standard protocols shared by the main italian laminopathies centers for the detection of prelamin A.
Source: Rabbit
Reacts with: Full-length prelamin A protein
Specificity: Anti-prelamin A polyclonal antibody detects full-lenght prelamin A which has not yet undergone proteolytic steps both in its non-farnesylated and in its farnesylated form. The farnesylated form of full-lenght prelamin A is labelled by the antibody with lower efficiency.
Recommended dilutions: Recommendedstarting dilutions can vary lot-to-lot. Consult the product information label in the package for lot specific values.
Note: When using any primary antibody or fluorescence-labelled secondary antibody for the first time, titrate out the antibody to determine which dilution allows the strongest specific signal with the lowest background for your sample.
For untested applications or species please refer to the S.M.A.K. program.
Purity: Purified by protein A affinity chromatography and conjugated by NHS-biotin.
Form: Liquid. Supplied in PBS and 0.05% v/v glycerol. Neutral pH.